This possibility is quickly shot down by their boss (David Hewlett), but that doesn't stop the headstrong Elsa from moving ahead, followed meekly by Clive. Clive and Elsa have plans to go beyond the creation of a pair of slug-like creatures that have excited their corporate sponsors - they want to do things with human DNA. They are led by Clive (Adrien Brody) and his girlfriend, Elsa (Sarah Polley), the masterminds behind a genetic splicing project that has pharmaceutical implications. The curtain rises on a small group of scientists feverishly working in a laboratory that seems decidedly behind-the-times technologically.
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There's a lot going on in the movie - some of which is rich, compelling material - but director Vincenzo Natali's scattershot approach to his subject matter leaves the viewer left with a frustrating sense that interesting paths were bypassed in service of a narrative that offers few surprises and concludes with a cornball, jarring sequence that belongs in another movie - perhaps the one being advertised by the aforementioned trailer. Despite its relative bravery in choosing not to embrace the Grand Guignol, Splice is a little too hit-or-miss to truly work. Like the vastly superior The Fly, it uses gore sparingly delivering shocks to the audience is a secondary consideration.
Splice is as much a psychological thriller and drama about bio-ethics as it is a horror movie.
However, although the film does indeed pilfer a scene directly from the latter movie, the trailer misrepresents its source. The trailer for Splice might lead a viewer to expect a low-budget retread of Species crossed with Aliens.
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